- October 4, 2019
- 11:00 a.m. - 12:00 p.m.
- Rudy North Lecture Theatre, LT 101, Lower Level, Djavad Mowafaghian Centre for Brain Health
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Organizer: Fidel Vila-Rodriguez, NINET lab and Dynamic Brain Circuits Cluster
Where: Rudy North Lecture room, lower level of Djavad Mowafaghian Centre for Brain Health (2215 Wesbrook Mall, Vancouver, BC -UBC Point Grey Campus).
When: Thursday, February 28th 9am to 12pm
Prof. Tim Murphy, representing the Dynamic Brain Circiuts Cluster, presented data at the Advances in Structural Imaging of Living Cells & Organisms: Focus on the Brain conference in Suzhou, China.
The Dynamic Brain Circuits Cluster helped host a Research Cluster exchange day on October 1st, 2018 with the Bionics Cluster, the Biomedical Imaging and Artificial Intelligence Cluster, the Designing for People Cluster, and the SmarT Innovations for Technology Connected Health (STITCH) Cluster.
Pictured: Dr. Matthew Farrer. Image credit: Paul Joseph/UBC.
For the past decade, Parkinson’s disease researchers have relied on the experimental equivalent of using a sledgehammer to tune a guitar to test new therapies for the disease. This may be a reason clinical trials of promising neuroprotective drugs fail. But, in new research published today in Nature Parkinson’s Disease, researchers at the Djavad Mowafaghian Centre for Brain Health (DMCBH) may have found the ideal tool for the job.
Pictured: wild-type and model neurons showing connection points. When the glycan associated with neurexin is absent fewer connection points exist, impairing communication within the brain.
For twenty years, researchers thought they knew everything there was to know about the composition of neurexin, a protein that connects neurons and is essential for communication within the brain. Neurexin is a key building block of synapses, the specialized sites where neurons connect and signal via chemical messengers.
For the brain to function, signals need to pass between neurons in order to control movement, speech, thought, and decision-making. Each individual neuron (there are billions within a single human brain) connects to a vast and complex network of neurons through thousands of synapses. Synapses mediate communication between neurons, affecting how we perceive and react to the world around us—essentially propelling us through life and making us who we are.
Pictured: Dr. Catharine Rankin delivers her talk C. elegans Automated Behavior Assays at NeuroFutures 2017 at the University of British Columbia. Photo credit: Dr. Jason Snyder.